Bioactive Small Molecules

A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.

Search Within Results

6,271 – 6,285 of 60,541 results

6,271

Medchemexpress LLC Benzonitrile, 3-fluoro-5-[3-(5-fluoro-2-pyridinyl)-1,2,4-oxadiazol-5-yl]- | 327056-26-8 | 99.9% | 284.22 | 50 MG

Benzonitrile, 3-fluoro-5-[3-(5-fluoro-2-pyridinyl)-1,2,4-oxadiazol-5-yl]- | 327056-26-8 | 99.9% | 284.22 | 50 MG

Pricing & Availability

6,272

Medchemexpress LLC Fazamorexant | 1808918-69-5 | C25H25FN4O2 | 100 MG

Fazamorexant is an orally active dual orexin receptor antagonist with an IC50 of 32 nM against OX1R and 41 nM against OX2R. It prolongs total sleep time and improves sleep efficiency, making it suitable for research on insomnia.

Orally active dual orexin receptor antagonist
Potently inhibits OX1R (IC50 = 32 nM) and OX2R (IC50 = 41 nM)
Prolongs total sleep time
Improves sleep efficiency
Applicable for research on insomnia
Selectively blocks OX1R and OX2R in vivo
Promotes rapid onset of sleep by inhibiting wake-promoting neurons

Pricing & Availability

6,273

Cayman Chemical 1-Palmitoyl-3-Linolenoyl-rac-glycerol, Purity: ≥98%, CAS: 126281-90-1, 5 mg

A diacylglycerol containing palmitic acid and α-linolenic acid at the sn-1 and sn-3 positions, respectively; has been found in the peel and pulp of unripe Dwarf Cavendish bananas

Pricing & Availability

6,274

Medchemexpress LLC HY-113004 50mg Medchemexpress, 3-Hydroxyvaleric acid CAS:10237-77-1 Purity:>98%

Medchemexpress, HY-113004 50mg 3-Hydroxyvaleric acid CAS:10237-77-1 3-Hydroxyvaleric acid is a 5-carbon ketone body. 3-Hydroxyvaleric acid is anaplerotic, meaning it can refill the pool of TCA cycle intermediates. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

Pricing & Availability

6,275

Cayman Chemical LXR-623, Purity: ≥98%, CAS: 875787-07-8, 1 mg

An LXR modulator that acts as a partial agonist at LXRα and a full agonist at LXRβ (IC50s = 179 and 24 nM, respectively); orally bioavailable and readily passes the BBB; anti-atherogenic in animal models of atherosclerosis

Pricing & Availability

6,276

Cayman Chemical IAXO-102, Purity: ≥95%, CAS: 1115270-63-7, 5 mg

A glycolipid TLR4 antagonist; inhibits lipid A-induced TLR4 activation in a cell-based assay (IC50 = 5.013 µM); reduces LPS-induced lethality in mice at 10 mg/kg; decreases angiotensin II-induced aortic expansion and rupture, as well as the incidence of abdominal aortic aneurysms, in ApoE-/- mice at 3 mg/kg

Pricing & Availability

6,277

Cayman Chemical DNP-INT, Purity: ≥98%, CAS: 69311-70-2, 10 mg

An electron transport inhibitor in plants; competitively inhibits plastoquinol oxidation by binding at the Qo site of cytochrome b6f (Kd = 1.4 nM); inhibits electron flow from water to NADP or methylviologen by 50 and 100% when used at concentrations of 0.5 or 5 µM, respectively

Pricing & Availability

6,278

Cayman Chemical Ac-WEAD-pNA (trifluoroacetate salt), Purity: ≥95%, 5 mg

A colorimetric caspase-1 and caspase-4 substrate; cleavage of the WEAD peptide sequence releases pNA, which can be quantified by colorimetric detection at 405 nm as a measure of caspase-1 and caspase-4 activity

Pricing & Availability

6,279

Cayman Chemical Z944, Purity: ≥98%, CAS: 1199236-64-0, 5 mg

A T-type calcium channel inhibitor (IC50s = 0.050-0.160 µM for human recombinant Cav3.1, Cav3.2, and Cav3.3); selective for T-type channels over the Cav2.2 channel (IC50 = 11 µM), as well as rat Cav1.2, hERG/Kv11.1, and human Nav1.5 channels (IC50s = 32, 7.8, and 100 µM, respectively); reduces seizure duration and the amount of time spent in seizures in a rat model of absence epilepsy at 30 mg/kg

Pricing & Availability

6,280

Cayman Chemical Ribitol, Purity: ≥98%, CAS: 488-81-3, 25 g

A pentose sugar alcohol; a component of the glycopolymer teichoic acid in bacterial cell walls; levels are increased in the brain, cerebrospinal fluid, urine, and plasma of a patient with RPI deficiency

Pricing & Availability

6,281

Medchemexpress LLC 1,10-bis(pyridinium)decane | 6266-40-6 | MFCD00031922 | 99.7% | 458.27 g/mol | C20H30Br2N2 | 5 MG

1,10-Bis(pyridinium)decane is a biscationic pyridinium salt used as a biochemical research reagent. It acts as an acetylcholinesterase (AChE) inhibitor with a reported IC50 of 25.8 nM and is supplied at high purity for in vitro pharmacology and enzymology studies. Available in milligram-scale quantities for laboratory use.

Bicationic pyridinium salt suitable for cholinesterase research
Reported AChE IC50 of 25.8 nM
High purity: 99.66%
Molecular weight: 458.27 g/mol
Chemical formula: C20H30Br2N2
Supplied in milligram-scale pack sizes for laboratory experiments
For research use only

Pricing & Availability

6,282

Medchemexpress LLC HY-B1272 100mg , Desipramine (hydrochloride) CAS:58-28-6 Purity:>98%

HY-B1272 100mg Desipramine (hydrochloride) CAS: 58-28-6 Desipramine hydrochloride is an inhibitor of norepinephrine transporter (NET), 5-HT transporter (SERT) and dopamine transporter (DAT) with Kis of 4, 61 and 78,720 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

Pricing & Availability

6,283

Cayman Chemical KX2-391, Purity: ≥98%, CAS: 897016-82-9, 100 mg

A Src kinase inhibitor (IC50 = ~20 nM); selective for Src over PDGFR, EGFR, JAK1, JAK2, Lck, and ZAP-70; induces cell cycle arrest at the G2/M phase and apoptosis in ERα-positive breast cancer cells; inhibits the growth of Huh7, PLC/PRF/5, Hep3B, and HepG2 cells (GI50s = 9, 13, 26, and 60 nM, respectively); decreases spleen weight and the number of splenic leukemia cells in a mouse model of FLT3-ITD-F691L AML

Pricing & Availability

6,284

Medchemexpress LLC Alpha-Gliadin (43-49) (Gliadorphin) | 107936-65-2 | MFCD00080188 | 99.8% | 875.97 | 50 MG

Alpha-Gliadin (43-49), also known as Gliadorphin, is a peptide that serves as the major protein component of gluten. This product can be utilized in studies involving the immunological response to alpha-gliadin.

Primary protein component of gluten
Inhibits the production of lymphokine activities by mononuclear leukocytes
Can be used in immunological response research to alpha-gliadin

Pricing & Availability

6,285

Apexbio Technology LLC Lomeguatrib 192441-08-0 50mg

Lomeguatrib (CAS 192441-08-0) is a potent inhibitor of O6-alkylguanine-DNA methyltransferase (MGMT) an enzyme involved in DNA repair that mitigates the cytotoxic effects of alkylating agents In MCF-7 cells Lomeguatrib inactivates MGMT with an approximate IC50 of 6 nM By suppressing MGMT activity Lomeguatrib sensitizes MGMT-expressing cell lines such as A375P and select mutBRAF and mutNRAS melanoma models to temozolomide but does not alter sensitivity to dacarbazine Clinical investigations have demonstrated dose-dependent inactivation of MGMT in patient-derived tumor tissues and peripheral blood mononuclear cells highlighting Lomeguatrib s value as a research tool for studying MGMT-mediated resistance mechanisms in cancer

Pricing & Availability

Bioactive Small Molecules

Filtered Search Results

Narrow Results

Medchemexpress LLC Benzonitrile, 3-fluoro-5-[3-(5-fluoro-2-pyridinyl)-1,2,4-oxadiazol-5-yl]- | 327056-26-8 | 99.9% | 284.22 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Fazamorexant | 1808918-69-5 | C25H25FN4O2 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-113004 50mg Medchemexpress, 3-Hydroxyvaleric acid CAS:10237-77-1 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 1,10-bis(pyridinium)decane | 6266-40-6 | MFCD00031922 | 99.7% | 458.27 g/mol | C20H30Br2N2 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-B1272 100mg , Desipramine (hydrochloride) CAS:58-28-6 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Alpha-Gliadin (43-49) (Gliadorphin) | 107936-65-2 | MFCD00080188 | 99.8% | 875.97 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More